- 18 Oct 2020
This however, is no vaccine, it is like a tool to reignite protection against the deadly virus. The cancer specialist informed that after the person is infected with this SARS COV-2, his/her immune system gets compromised and it is very important for its strength to be brought back so that body can develop anti bodies for protection against the virus. Thus, your body becomes the Kurukshetra and the COVID-19 hence, is an army of Shakunis of this Mahabharata.
Dr. VishaL Rao and his team claims to have cracked the treatment puzzle for COVID-19. “We have built a concoction of cytokines which can be injected to reactivate the immune system in COVID-19 patients” said Dr. Rao in his interview to news agency ANI.
The research is still in its initial phase and the first set and should be ready by this week. Dr. Rao also informed that he has also applied for an expedited review with ICMR and waiting for approval. This however, is no vaccine, it is like a tool to reignite protection against the deadly virus.
Dr. Vishal Rao is an oncologist in Bengaluru, who is famous for inventing a voice prosthesis device costing as low as Rs 50, helping throat cancer patients speak.The cancer specialist informed that after the person is infected with this SARS COV-2 , his/her immune system gets compromised and it is very important for its strength to be brought back, so that body can develop anti bodies for protection against the virus. Ultimately, it is one’s own body that fights the virus, any medicine or vaccine only acts like a catalyst.
A systematic biological study examined the differences in the age-specific mortality of SARS and the most important signaling pathways activated by the COV-2 virus due to its similarities with SARS COV.
The Sars-Cov-2 is more contagious due to the pointed spike proteins which bind easily to the molecule “angiotensin-converting enzyme 2” (ACE2), often receptors in the lungs. The virus injects its RNA in to the cells and damages their core and orders them to self destruct, replicating itself in the process and using the cells. Thus, an exponential increase in such cells makes one sick and it takes 14 days to show symptoms.
The cells of the body have cytokines which have immune substances like interferons. The cytokines are released by immune cells in the body to counter this immune response. Cytokines are signalling proteins and immune cells are like weaponized bots who work on instructions. The immune cells have two major types, neutrophils and the killer T cells. The virus also infects them when they come to destroy the infected cells. The COV-2 is a very smart virus and it also send wrong signals to cytokines, as a result cytokines signals more immune cells to come than required. The virus thus turn immune cells against each other. The infected neutrophils secretes enzymes which kills the healthy cells, and the T cells orders healthy cells to commit suicide in the confusion created by this cunning virus. Thus, your body becomes the Kurukshetra and the COVID-19 hence, is an army of Shakunis of this Mahabharata.
It was found that interferons possess a crucial role in the defense against all sorts of coronavirus diseases. The virus has been seen to restrict the movement of the interferons (signaling proteins that are released by cells to counter different viral responses) in humans. The interferon’s have a protein called STATI which the virus doesn’t seem to like much. The differences observed in the dynamics of interferon’s in adults, children and the elderly may also explain the difference in fatality rates of the COVID-19.
If interferon-inducing agents, such as Poly (ICLC) are administered, they may reduce the mortality of SARS diseases at the very early stages. These injected cytokines can send the right signals to the immune cells and hence the immune system may be revived. The addition of interferon-y to an interferon-I can work as a synergistic combination therapy to inhibit the motives of COVID-19 virus. Dr. Rao and team are very positive and if their research is approved by the government, we may finally have the medicinal cure to this virus in true sense.