- 16 May 2022
While the whole world is struggling to deal with the havoc created by the ‘coronavirus’. Every medical institute across the world is running a race to develop a vaccine for this detrimental sickness. Amid all this battle between the humans and virus, India got a ray of hope when all woke up to the news of getting a potential vaccine to overcome any more damage to the human life.
Winning the race of clinical trials, COVAXIN, India's first original COVID-19 vaccine is established in by the Hyderabad based firm Bharat Biotech India in collaboration with the Indian Council of Medical Research (ICMR) and National Institute of Virology. The indigenous, inactivated vaccine is developed and produced in Bharat Biotech's BSL-3 high containment space (Bio-Safety Level 3).
The DCGI (Drug Controller General of India) gave the approval for Phase I & II Human Trials and the trials were to begin from July, 2020 across the country. Covaxin will be tested on 375 people in phase 1 trial and 750 in the next phase, overall covering more than 1000 people under this phase. On the basis of the results, further developments will be made. Also, ICMR aims to release the vaccine for public use by August,2021.
Why is Covaxin termed as inactivated vaccine? How does the vaccine work?
- Covaxin has been termed as inactivated, these are the vaccines which use the dead versions of the viruses and germs that cause diseases.
- It is made from the dead particles of the SARS-CoV-2 which will disable the virus from infecting or replicating. Once this is injected in the body of the healthy individuals, it will produce antibodies within and help to fight the foreign cells entering into the system.
- Inactive vaccines do not impart whole life protection, so one will require to take recurrent doses of vaccines after a specific period of time.
But, the good news is that they are safe and do not have any side effects. Therefore, just like other diseases such as flu, polio and rabies, coronavirus is expected to be the next add on to the list. Just hoping to get positive results from the human trials. Our corona warriors have been working day and night to win this hard warfare.
Among the 12 medical institutes, selected by the ICMR, AIIMS PATNA is set to begin the trials this week. The uplifting news is that this vaccine has already cleared the animal trials and is expected to emerge successfully in the humans as well. The estimated time frame for the trials is 6-8 months. However, the orders have already been given to make this project a top priority and declare faster results. The kick start has already been given and being optimistic in this situation is the only strength that can work for us.
Globally, there are many vaccines which are undergoing different phases of trials and tribulations. Moderna and AstraZeneca are in to phase 3 of human trials.
It is decided that the trials will be done on individuals between the age group 22 years and 50 years. Even the global authorities are going on for the trials for the same age group. This may be a concern as the vaccines are focusing more on the younger and we are nowhere close to develop vaccines for people older than 65 or 70. It is yet to be looked at if the devised vaccine will provide enough immunity to the old age group. Let us wish for the best!