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A favourable outcome: Russia the first country to perform a successful clinical trial of the COVID vaccine

  • Team PresentMirror | Updated: July 25, 2020, 6:46 p.m.


Russia became the first country to attain clinical trials of the Covid-19 vaccine. Reports say that the medications were seen to be effective, andno side effects are observed till date. Trials of two forms of a potential Covid-19 vaccine from the Gamaleya National Research Center for Epidemiology and Microbiology were allowed on June 18.


Image Credit: Prensa Latina

The trials of first vaccine, which exist in the form of a solution for intramuscular administration, were carried out at the Burdenko Military Hospital. The trials of other vaccine (powdered form for the preparation of a solution for intramuscular administration), was carried out at Sechenov First Moscow State Medical University.

The first stage of research at Sechenov University involved a group of 18 volunteers and the second involved 20 volunteers. After vaccination, all volunteers had to remain in a 28 days of isolation in a hospital. The results demonstrated that they were developing immunity towards corona virus.

Covid-19 Pandemic:

Coronavirus disease 2019 (COVID-19): an infectious disease caused by novel coronavirus (SARS-CoV-2), was first identified in December 2019 in Wuhan, Hubei, China. The first confirmed case traces back to 17 November 2019 in Hubei. Since then the COVID-19 has taken the world to a pandemic situation, infecting more than 15 million people and more than 6 lakh fatalities. According to World Health Organisation (WHO), there are at least 21 vaccines currently under key trials.


Common symptoms include high fever, cough, fatigue, shortness of breath, loss of smell and taste. Majority of cases result in mild symptoms, but some cases lead to acute respiratory distress syndrome (ARDS), possibly precipitated by cytokine storm, multi-organ failure, septic shock, and blood clots. The onset time for symptoms from exposure is typically 3-5 days, but may range from 2-14 days. However there are also cases with no symptoms at all.

Vaccine race:

The entire world is racing for vaccine to check the spread of the coronavirus disease. Researchers around the world are working tirelessly to find a vaccine for COVID-19. There are more than 130 candidates of COVID-19 vaccines globally with countries like US, Russia, China, UK, India and Israel leading the chart.

The procedure of the trial:

• Phase 1 normally involves small-scale studies to determine a candidate vaccine's clinical tolerance and safety.

• Phase 2 includes a larger number of subjects, with a focus on determining the optimal dose, intervals between doses, and the minimum necessary number of doses of a candidate vaccine in a target population.

• Phase 3 trials are the largest in terms of a number of subjects. Anindividual's vaccine is ready to move into industrial production if the last phase provides clear and definitive evidence of its safety and efficacy.

Russia’s Plan for COVID Vaccine:

The head of Russia’s sovereign Wealth Fund announced that Russia plans to supply 30 million doses of the experimental coronavirus vaccine this year itself, with the possibility of producing 170 million overseas. According to reports, Russian scientists professed on Monday that they hope to launch the world’s first coronavirus experimental vaccine as soon asnext month.

Kirill Dmitriev, head of the Russian Direct Investment Fund (RDIF), announced that a larger trial of the third phase, including numerous thousand people, would begin in August. “We believe based on current results, it will be approved in Russia in August and some other countries in September, which may become the world’s first approved vaccine”, Mr. Dmitriev was quoted saying.

On Wednesday, The Russian Defense Ministry announced that it has developed a safe vaccine against the pandemic COVID-19, which is known as SARS-CoV-2.

At the same time, the World Health Organization agreement says that the vaccine must go through three stages of research before it can be approved for mass production. Besides this, the WHO coronavirus vaccine outlook project lists the study of Russian vaccine candidates as the first phase of trials.

So far, perhaps no vaccine has been approved for mass use without passing the third phase of testing, which is the phase with the largest number of the partaker.

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